101. Isolated diastolic vs. systolic hypertension phenotypes and outcomes: prospective cohort of newly diagnosed individuals with hypertension.
Thomopoulos C, Andrikou I, Konstantinidis D, Iliakis P, Kalos T, Polyzos D, Drogkaris S, Siafi E, Tousoulis D, Stergiou GS, Tsioufis C.
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102. Opportunistic screening for hypertension in the general population in Greece: International Society of Hypertension May Measurement Month 2019.
Stergiou GS, Menti A, Doumas M, Gkaliagkousi E, Grassos C, Kalaitzidis RG, Kallistratos MS, Katsi V, Krokidis X, Makris T, Manios E, Manolis A, Marketou M, Papadakis JA, Papadopoulos D, Protogerou A, Chatzopoulos M, Sarafidis P, Tsioufis C, Zebekakis P.
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Hypertension remains a major public health issue with inadequate control worldwide. The May Measurement Month (MMM) initiative by the International Society of Hypertension was implemented in Greece in 2019 aiming to raise hypertension awareness and control. Adult volunteers (≥18 years) were recruited through opportunistic screening in five urban areas. Information on medical history and triplicate sitting blood pressure (BP) measurements were obtained using validated automated upper-arm devices. Hypertension was defined as systolic BP ≥140 mmHg and/or diastolic ≥90 mmHg, and/or self-reported use of drugs for hypertension. A total of 5727 were analysed [mean age 52.7 (SD 16.6) years, men 46.5%, 88.3% had BP measurement in the last 18 months]. The prevalence of hypertension was (41.6%) and was higher in men and in older individuals. Among individuals with hypertension, 78.7% were diagnosed, 73.1% treated, and 48.3% controlled. Awareness, treatment, and control of hypertension were higher in women and in older individuals. Hypertensives had a higher body mass index (BMI) and were more likely to have diabetes, myocardial infarction and stroke, and less likely to smoke than normotensives (all
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103. May Measurement Month 2019: results of blood pressure screening from 47 countries.
Poulter NR, Borghi C, Damasceno A, Jafar TH, Khan N, Kokubo Y, Nilsson PM, Prabhakaran D, Schlaich MP, Schutte AE, Stergiou GS, Unger T, Beaney T.
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104. 'Apples to oranges' and 'Less is more'.
Argyris AA, Samara S, Blacher J, Papaioannou TG, Stergiou GS, Vlachopoulos C, Wassertheurer S, Weber T, Protogerou AD.
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105. Joint ESH excellence centers' national meeting on renal sympathetic denervation: A Greek experts' survey.
Doumas M, Andreadis E, Andronoglou M, Davlouros P, Dimitriadis K, Gkaliagkousi E, Grassos H, Hatzitolios A, Iliakis P, Kalaitzidis R, Kallistratos E, Kasiakogias A, Konstantinidis D, Kotsis V, Makris T, Manolis A, Moulias A, Marketou M, Papadakis I, Papadopoulos D, Poulimenos L, Sanidas E, Sarafidis P, Savopoulos C, Stergiou G, Tatakis F, Thomopoulos K, Triantafyllidi H, Triantafyllou A, Vlachakos D, Zebekakis P, Ziakas A, Papademetriou V, Tsioufis C.
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106. Nighttime Home Blood Pressure in Children: Association with Ambulatory Blood Pressure and Preclinical Organ Damage.
Stambolliu E, Kollias A, Bountzona I, Ntineri A, Servos G, Vazeou A, Stergiou GS.
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107. Opportunistic screening for hypertension: what does it say about the true epidemiology?
Menti A, Kalpourtzi N, Gavana M, Vantarakis A, Voulgari PV, Hadjichristodoulou C, Gkaliagkousi E, Doumas M, Kalaitzidis RG, Kallistratos MS, Karakosta A, Katsi V, Krokidis X, Manios E, Marketou M, Ntineri A, Papadakis JA, Papadopoulos D, Sarafidis P, Trypsianis G, Chatzopoulos M, Chlouverakis G, Alamanos Y, Zebekakis P, Touloumi G, Stergiou GS.
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This study aimed to assess the reliability of opportunistic screening programs in estimating the prevalence, treatment, and control rate of hypertension in the general population. Two recent epidemiological surveys obtained data on hypertension in the adult general population in Greece. The EMENO (2013-2016) applied a multi-stage stratified random sampling method to collect nationwide data. The MMM (2019) collected data through opportunistic (voluntary) screening in five large cities. Hypertension was defined as blood pressure (BP) ≥ 140/90 mmHg (single occasion; average of 2nd-3rd measurement; electronic devices) and/or use of antihypertensive drugs. Data from a total of 10,426 adults were analyzed (EMENO 4,699; MMM 5,727). Mean age (SD) was 49.2 (18.6)/52.7 (16.6) years (EMENO/MMM, p < 0.001), men 48.6/46.5% (p < 0.05) and body mass index 28.2 (5.7)/27.1 (5.0) kg/m
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108. Venous thromboembolism in COVID-19: A systematic review and meta-analysis.
Kollias A, Kyriakoulis KG, Lagou S, Kontopantelis E, Stergiou GS, Syrigos K.
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Severe coronavirus disease 2019 (COVID-19) is associated with increased risk of venous thromboembolism events (VTE). This study performed a systematic review in PubMed/EMBASE of studies reporting the prevalence of VTE in patients with COVID-19 who were totally screened/assessed for deep vein thrombosis (DVT) and/or for pulmonary embolism (PE). Among 47 candidate studies (
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109. 2021 European Society of Hypertension practice guidelines for office and out-of-office blood pressure measurement.
Stergiou GS, Palatini P, Parati G, O'Brien E, Januszewicz A, Lurbe E, Persu A, Mancia G, Kreutz R.
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110. Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight.
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From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of underweight, obesity, and severe obesity in different regions using data from 2896 population-based studies with 187 million participants. Changes in the prevalence of underweight and total obesity, and to a lesser extent severe obesity, are largely driven by shifts in the distribution of BMI, with smaller contributions from changes in the shape of the distribution. In East and Southeast Asia and sub-Saharan Africa, the underweight tail of the BMI distribution was left behind as the distribution shifted. There is a need for policies that address all forms of malnutrition by making healthy foods accessible and affordable, while restricting unhealthy foods through fiscal and regulatory restrictions.
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111. Prospective meta-analysis protocol on randomised trials of renin-angiotensin system inhibitors in patients with COVID-19: an initiative of the International Society of Hypertension.
Gnanenthiran SR, Borghi C, Burger D, Charchar F, Poulter NR, Schlaich MP, Steckelings UM, Stergiou G, Tomaszewski M, Unger T, Wainford RD, Williams B, Rodgers A, Schutte AE.
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112. Blood pressure and outcome in patients with atrial fibrillation: floating in uncharted waters.
Kyriakoulis KG, Kollias A, Stergiou GS.
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113. Reproducibility of Office and Out-of-Office Blood Pressure Measurements in Children: Implications for Clinical Practice and Research.
Stergiou GS, Bountzona I, Alamara C, Vazeou A, Kollias A, Ntineri A.
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This study aimed to evaluate the reproducibility of office (OBP), ambulatory (ABP), and home blood pressure (HBP) measurements in children and adolescents, and their implications in diagnosing hypertension in clinical practice and in pediatric hypertension research. Apparently healthy children and adolescents referred for suspected hypertension were included. Measurements of 2-visit OBP, 7-day HBP, and 24-hour ABP were performed twice, 1 to 6 months apart. Reproducibility was quantified using the SD of differences between repeated measurements. The sample size of clinical trials comparing the efficacy of antihypertensive drugs using each method was calculated. Fifty-eight individuals were analyzed (mean age, 13.0±2.9 years, 60.3% boys). The reproducibility of 24-hour ABP (SD of differences 5.7/4.5 systolic/diastolic) and HBP (5.9/5.0 mm Hg) were comparable and superior to that of visit-2 OBP (9.2/7.8) and awake (6.7/5.5) or asleep ABP (7.6/6.1). As a consequence, a parallel-group comparative trial aiming to detect a difference in the effect of 2 drugs of 10 mm Hg systolic BP, would require 36 participants when using OBP measurements, 14 using 24-hour ABP, and 15 using HBP (102/34/42 respectively for detecting a 5 mm Hg difference in diastolic BP). For a crossover design trial, the corresponding sample sizes are 9/3/4 for systolic BP and 26/9/11 for diastolic, respectively. These data suggest that in children and adolescents 24-hour ABP and 7-day HBP have similar reproducibility, superior to OBP and daytime or asleep ABP. These findings have major implications in diagnosing hypertension in children in clinical practice and in designing clinical research trials in pediatric hypertension.
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114. Anticoagulation therapy in COVID-19: Is there a dose-dependent benefit?
Kollias A, Kyriakoulis KG, Syrigos NK, Stergiou GS.
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115. Anticoagulant selection in relation to the SAMe-TT
Ntaios G, Huisman MV, Diener HC, Halperin JL, Teutsch C, Marler S, Gurusamy VK, Thompson M, Lip GYH, Olshansky B.
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116. Validation of the single-cuff oscillometric blood pressure monitor InBody BPBIO750 for public spaces according to the Association for the Advancement of Medical Instrumentation/European Society of Hypertension/International Organization for Standardization Universal Standard.
Ntineri A, Prapa S, Bountzona I, Menti A, Stergiou GS.
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117. Prevalence, awareness, treatment and control of hypertension in Greece: EMENO national epidemiological study.
Stergiou GS, Menti A, Kalpourtzi N, Gavana M, Vantarakis A, Chlouverakis G, Hajichristodoulou C, Trypsianis G, Voulgari PV, Alamanos Y, Karakosta A, Touloumi G.
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118. Clinical hypertension research in patients with atrial fibrillation: At last!
Kollias A, Kyriakoulis KG, Stergiou G.
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119. Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants.
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120. High prevalence of cardiovascular risk factors in adults living in Greece: the EMENO National Health Examination Survey.
Touloumi G, Karakosta A, Kalpourtzi N, Gavana M, Vantarakis A, Kantzanou M, Hajichristodoulou C, Chlouverakis G, Trypsianis G, Voulgari PV, Alamanos Y, Makrilakis K, Liatis S, Chatzipanagiotou S, Stergiou G.
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